DNMT1 and infection: As shown in Figure 2a, infection with MS caused highly significant downregulation of DNMT1 expression compared to both the negative control and MAH at 4 h p.i. (mean fold difference to negative control: 0.48, unpaired t-test, p < 0.001), as well as 8 h p.i. (mean fold difference to negative control: 0.31, unpaired t-test, p < 0.001), whereas infection with MAH only caused slightly decreased DNMT1 expression 4 h p.i. (mean fold difference to negative control: 0.76) and 8 h p.i. (mean fold difference to negative control: 0.69, unpaired t-test, p < 0.05).