Bearing in mind our detection of positive associations between the umbilical cord serum FABP4 level and the maternal serum FABP4 and leptin levels (as well as previous results regarding the relationship between these “inauspicious”/proinflammatory adipokines and the pathogenesis of T2DM, obesity, cardiovascular diseases, and metabolic syndrome), a consideration of FABP4 and leptin in future studies of GDM offspring seems to be of the essence. This evidence concerns the gene FABP4 and type 2 diabetes mellitus.