We focused this study on two members of the family, p62 and optn, which are transcriptionally induced during Mm infection of zebrafish based on published RNA sequencing data [27] and show strong similarity with their human orthologues in the ubiquitin-binding domains (UBA in p62 and UBAN in Optn) and Lc3 interaction regions (LIR) (S1B Fig). The gene discussed is MAP1LC3A; the disease is infection.