ABCG1 and lung cancer: Macrophages with ABCG1 expression undertake a tumor promoting phenotype, M2, and have been associated with tumor growth and antiapoptosis.[32] ABCG1 expression in macrophages is also associated with poor survival outcomes in patients with lung cancer.[33, 34] Accordingly, a polymorphism in ABCG1 that was related to higher ABCG1 expression (rs225388) was associated with poor survival in patients with lung cancer.[35] Another SNP (rs492338) was strongly associated with paclitaxel-induced neuropathy,[36] but this SNP was not associated with outcome in our study.