Since variants in the gap junction protein beta 2 gene (GJB2) were firstidentified as causative of ARNSHL in 1997 (Kelsellet al., 1997), to date (January, 2019), at leastpathogenic variants in other 72 genes have been causally associated with ARNSHLaccording to the Hereditary Hearing Loss Homepage(https://hereditaryhearingloss.org). Here, GJB2 is linked to hearing loss disorder.