PNPLA2 and Familial prostate cancer: In contrast, less aggressive prostate cancer cells, LNCaP, appeared less metabolically active in the TAG pathway compared to PC-3 cells, showing a lower expression of both ATGL (LNCaP vs PC-3: 38.5 ± 1.5 vs 136.6 ± 1.6; P < 0.001) and DGAT1 (LNCaP vs PC-3: 132.6 ± 1.5 vs 165.6 ± 1.5; P < 0.01) proteins.