In a previously reported case-control study within the AIDS Clinical Trials Group (ACTG) Longitudinal Linked Randomized Trials (ALLRT) cohort, soluble markers of inflammation (IL-6, sTNFR-I/II) and coagulation (D-dimer) measured 1 year after ART initiation were associated with subsequent non-AIDS events, but T-cell activation was not [10]. This evidence concerns the gene IL6 and AIDS.