The TEx and TMv with modified content, referred to here generally as mTEx and mTMv, were obtained from genetically engineered murine colon carcinoma MC38 cells with overexpression of IL-12 and/or shRNA for TGF-β1 (MC38/IL12, MC38/shTGFβ1, or MC38/IL12shTGFβ1). The gene discussed is TGFB1; the disease is colon carcinoma.