In a 2012 meta-analysis, autoimmune thyroiditis, as well as overall thyroid antibody positivity, thyroglobulin antibody positivity and thyroid peroxidase antibody (TPOAb) positivity were associated with increased risk of breast cancer (OR 2.92, 2.02, 2.72, 2.64, respectively), with minimal to moderate heterogeneity (139). The gene discussed is TG; the disease is breast carcinoma.