First, patients with higher SD-HbA1c values had increased body weight and body mass index, higher mean and index HbA1c values, higher triglyceride and uric acid levels, higher urinary albumin excretion and albumin-creatinine ratios, an increased proportion of insulin therapy and prevalence of hypertension and metabolic syndrome, and lower eGFR. This evidence concerns the gene INS and hypertensive disorder.