ADAMTS6 and lung cancer: Finally, survival analysis of lung cancer patients using the kmplot.com software showed that a high expression of genes involved in ECM degradation, such as ADAM19 (p = 3.3E−5), ADAMTS6 (p = 0.00032), or MMP9 (p = 0.04), was associated with a poor prognosis (Supp Fig. 10).