Sixteen days after subcutaneous injection of BxPC-3 into nude mice, the sh-AGAP2-AS1 group showed a markedly lower speed of tumor growth compared with the empty vector group (Fig. 6A), as well as reduced tumor volume and weight (Fig. 6b, c), indicating that AGAP2-AS1 regulates PC cell proliferation in vivo. Here, AGAP2 is linked to neoplasm.