AGAP2 and pachyonychia congenita: We performed a chi-square test to compare the clinicopathological features of the two groups and obtained the data shown in Table 1; the upregulation of AGAP2-AS1 expression in PC tissues was significantly associated with tumor size (P = 0.0010), late TNM staging (P = 0.0020), and lymph node metastasis (P = 0.0020) in PC patients.