As shown in Fig. 2a, the expression levels of AGAP2-AS1 in human PC BxPC-3, SW1990, and PANC-1 cells, and in the human metastatic PC cell line AsPC-1, were higher than those in human normal pancreatic ductal epithelial cells (HPDE6-C7). Here, AGAP2 is linked to pachyonychia congenita.