For HL patients, the highest diagnostic accuracy was reported for MCP-1 and IL-6 (93.75, 90.63%, respectively) Sn (91.7% each) and Sp (95.05, 90.0%, respectively) at indicated cut-off values >9.38 and >9.59 pg/ml, respectively. The gene discussed is IL6; the disease is Hodgkins lymphoma.