On the other hand, MCP-1 expression was completely absent in the trabecular bone near the tumor in mice inoculated with MDA-MB-231GFP/Luc2 cells alone (0% of cells), while some MCP-1 expression was observed in the trabecular and cortical bones of tumor-bearing mice injected MDA-MB-231GFP/Luc2 cells plus either MC3T3-E1 cells (~ 16% of cells) or EO-231 cells (~ 1% of cells) (Fig. 3). This evidence concerns the gene CCL2 and neoplasm.