TNF and neoplasm: Moreover, we provided first evidence for the involvement of members of the TNF family in platelet-mediated evasion of tumor cells from NK cell reactivity: we showed that platelets transfer glucocorticoid-induced TNFR-related ligand (GITRL) to tumor cells, which results in diminished antitumor immunity due to triggering the GITR receptor that is expressed on and inhibits reactivity of NK cells [16].