In this context, the rs6920220 SNP, located in a noncoding region upstream of TNFAIP3, has been linked to an increased risk of rheumatoid arthritis [31,32,33], lupus erythematosus [34], type II psoriasis [35], Sjögren’s syndrome [36], and type I diabetes [37]. This evidence concerns the gene TNFAIP3 and Sjogren syndrome.