Indeed, we found the synthetic 36 aa ALK-derived peptide (P36) that mimics the ADD domain of ALK was specifically inducing apoptosis in a caspase-dependent fashion in ALK-positive ALCL and ALK-expressing neuroblastoma cells, but not ALK-negative cancer cell lines and normal peripheral blood mononuclear cells [89]. Here, ALK is linked to anaplastic large cell lymphoma.