EML4 and non-small cell lung carcinoma: For instance, ALK translocations or inversions are frequent in inflammatory myofibroblastic tumors (IMT) (50–60%), and 4–8% of non-small cell lung cancer (NSCLC) carry an echinoderm microtubule-associated protein-like 4 (EML4)-ALK fusion due to an (2)(p21;p23) inversion.