BRAF and colorectal carcinoma: While right-sided EOCC is linked with CIMP-High and a low prevalence of somatic CNAs or CIN, right-sided LOCC showed BRAF mutation, high grade of differentiation, predominance in females, and worse survival after relapse, in agreement with recent studies showing worse prognosis of patients with MSI and recurring BRAF-mutant CRC [23,24,25].