However, in a subgroup of the clopidogrel as adjunctive reperfusion therapy-thrombolysis in myocardial infarction 28 (CLARITY-TIMI 28) trial, involving STEMI patients, Sabatine et al. created a multimarker model with sST2, NT-proBNP, and traditional cardiovascular risk factors. This evidence concerns the gene NPPB and myocardial infarction.