ANGPT1 and leukemia: Other current studies have shown that leukemia-regenerating cells (LRCs) arise post-chemotherapy and are distinct from LSCs identified at diagnosis: LRCs emerge following chemotherapy treatment and are characterized by a peculiar pattern of gene expression, with high expression of dopamine receptor D2 (DRD2) and human serotonin receptor 1B (HTR1B) and of angiopoietin-1 [401].