LDHA and metastatic neoplasm: We also carried out an assessment of metastatic disease, comparing the incidence of metastasis in control TRAMP (Ldha-intact) to that in Ldha-knockout TRAMP, concentrating on several typical sites of disease spread: regional periaortic lymph nodes (PALN), the more distant perirenal lymph nodes (PRLN), and visceral metastases (liver and lung).