ERN1 and lung carcinoma: About this, it has recently been shown that an ethyl acetate extract from Scindapsus cf. hederaceus (SH-EAE), by decreasing the expression of PERK and IRE1α, exerts anti-proliferative and anti-migratory activities in human lung cancer cells; moreover experiments in zebrafish demonstrated that a decreased expression of PERK and IRE1α in SH-EAE-treated lung cancer cells is accompanied by the reduction of vessels development, suggesting an antiangiogenic effect [131].