CALR and cancer: The profile of biomarkers analyzed by these investigators is extensive and includes various DAMPs, autoantibodies to CRT and HSP90, indoleamine-2,3-dioxygenase, protumorigenic and antitumorigenic chemokines/cytokines, as well as serum-associated exosomes, the latter representing a recent innovation in the detection of exosomal, cancer-associated microRNAs [140].