Moreover, while another proposed indicator of adipose tissue dysfunction, namely VAI, was better correlated with glucose and lipid metabolism markers (taking into consideration that is calculated from anthropometric and lipid variables), the Adpn/Lep ratio was better correlated with BMI, waist circumference and blood pressure, as well as with markers of systemic inflammation and hepatic steatosis. The gene discussed is ADIPOQ; the disease is fatty liver disease.