CD274 and adenocarcinoma: In addition, our results showed that the expression of PD-L1 Tii was not significantly correlated with the infiltration of CD68-expressing cells during the neoplasia and adenocarcinoma stage (P = .0567), whereas Kazuto Harada et al[27] considered that PD-L1 expression was positively correlated with the infiltration of CD68-positive cells.