Changes in α-skeletal actin (Acta1–6 fold increase), atrial natriuretic peptide (Nppa– 1.9 fold increase), brain natriuretic peptide (Nppb– 2.6 fold increase), cardiac troponinT (cTnT– 14% decrease), consistent with expected molecular signature of heart failure. Here, ACTA1 is linked to heart failure.