IL: Interleukin; TNF: tumor necrosis factor; TGF: transforming growth factor; MMP: metalloproteinase; RANK: Receptor activator of nuclear factor kappa; OPG: Osteoprotegerin; T1: initial examination; T2: final exam; n: individuals; MP: peri-implant mucositis; PI: peri-implantitis; SD standard deviation. Here, TNF is linked to Peri-Implantitis.