The PPP is important in promoting cancer proliferation, differentiation and survival.27 Overexpression of G6PD is a prognostic factor in multiple cancers and is associated with tumour progression, metastasis or recurrent disease.28 The oxidative PPP converts G6P, a glycolytic intermediate, into ribulose‐5‐phosphate and generates NADPH, which is used for GSH production, detoxification and biosynthesis of lipids. This evidence concerns the gene G6PD and neoplasm.