TNF and early-onset autosomal dominant Alzheimer disease: As shown in Figure 6(d) and Table s5, the KEGG analysis indicated that the lncRNA were involved in the inflammation progress (NF-kappa B signaling pathway, TNF signaling pathway, Inflammatory mediator regulation of TRP channels, and cell adhesion molecules (CAMs)) and neuronal function or nervous system diseases (Alzheimer's disease, Huntington's disease, neuroactive ligand-receptor interaction, and synaptic vesicle cycle).