However, when the two groups of xenograft tumors were subjected to local radiation at a single dose of 6 Gy, we found that the sh-LOXL2 group of mice were more sensitive to treatment, with a significant shrinkage in tumor volume in the sh-LOXL2 group as compared with that in the sh-scramble group, as shown in Figure 4(b). The gene discussed is LOXL2; the disease is neoplasm.