Of the downregulated proteins, metabolic pathways (43, 30.07%), microbial metabolism in diverse environments (25, 17.48%), focal adhesion (19, 13.29%), regulation of actin cytoskeleton (13, 9.09%), glycolysis/gluconeogenesis (13, 9.09%), tight junction (11, 7.69%), protein processing in endoplasmic reticulum (10, 6.99%), pathways in cancer (9, 6.29%), neurotrophin signaling pathway (8, 5.59%), and MAPK signaling pathway (8, 5.59%) were involved in the DTMUV-infected DEFs at 42 hpi (Figure 4(c)). This evidence concerns the gene BDNF and cancer.