TACC1 and acquired factor X deficiency: They were distributed in a non-recurrent pattern involving 5q21.3 (FER), 8p11.22-23 (FGFR1, TACC1) and 13q34 (LAMP1) in AFX, and 11q13.3 (CCND1) and 12q24.31 (KNTC1) in PDS (Additional file 4: Figure S2).