Systemic irradiation of mice with LR enhanced the pulmonary levels of both TNF-α (Figure 6B) and IFNγ (Figure 6C) indicating pulmonary fibrosis in these mice as cellular damage upon irradiation is known to result in cytokine-mediated induction and progression of inflammatory and fibrotic tissue reactions (33, 34). The gene discussed is IFNG; the disease is pulmonary fibrosis.