MPPE1 and neoplasm: Administration of recombinant FLT3-L to tumor-bearing mice as a supportive treatment to mAIM immunotherapy reinforces CTL infiltration and activation in the tumor (137), and the combined administration of FLT3-L and poly(I:C) which respectively support cDC1 expansion and activation significantly improved antitumor mAIM immunotherapy in mice (79, 118) (Table 4).