ZC3H12A and metabolic dysfunction-associated steatotic liver disease: Interestingly, LSECs’ pro-inflammatory activation was compensated by MCPIP1 mRNA overexpression (Figure 3E) and increased secretion of anti-inflammatory PGI2 (measured as 6-keto-PGF1α) and PGD2 (Figure 4C,D) in the late, but not in the early stage of NAFLD.