CYP3A4, APOA2, PPARG, ALOX, and CYP4F2, proteins related to lipid homeostasis affect the occurrence of hypertension, and PTGER2, ALOX5, LTF, ITGB, and GATA3 relate to the inflammatory and immune response in glomeruli. The gene discussed is CYP3A4; the disease is hypertensive disorder.