SATB2 and SATB2 associated disorder: To better understand SAS, particularly its autistic and behavioral symptoms, we generated Satb2 CKO mice in which Satb2 was deleted in the cerebral cortex and hippocampus, which are two major brain regions with high levels of Satb2 expression (Huang et al., 2013a) and are likely to be involved in the SAS-related behavioral phenotypes.