CBLIF and neoplasm: They share many common features with Tcyt cells, but in in contrast to Tcyt cells, they can kill cells lacking the self-recognition marker major histocompatibility complex 1 without further activation.65 NK cells also produce cytokines such as INFɣ that activate other immune cells, including M1 macrophages.11,66 This supports the NK cells’ role as potent tumour suppressors and putative prognostic markers.