S100A8 and neoplasm: Further analysis using xCell method revealed the maximum correlation of transcripts of high abundant serum proteins, including S100A8 and S100A9, with myeloid lineage and a negative correlation with cells signature of lymphoid lineage, suggesting the presence of higher levels of S100A8 and S100A9 transcript in tumor tissue can serve as indicator of a biased myeloid differentiation of tumor micro and macroenvironment.