HSPA5 and neoplasm: Interestingly, barely detectable tumor Luc signals were observed in mice treated with combination of TMZ with RGD4C/AAVP‐Grp78‐HSVtk plus GCV compared to mice administered with RGD4C/AAVP‐Grp78‐HSVtk plus GCV or TMZ alone (Fig 8A).