As shown in Fig. 5b and Additional file 3, the tracer signal was detectable at the tumor site; however, the tumor uptake was usually only moderate, and in none of the experiments could we detect statistically significant differences between non-depleted mice and CD122-depleted mice (Fig. 5c), although CD122+ TILs were usually successfully depleted in mice injected with the CD122-depleting antibody (see Fig. 5a). The gene discussed is IL2RB; the disease is neoplasm.