H19 and fetal growth restriction: The three samples with hypomethylation of the H19 ICR (PL67, 90, 217) were all from pregnancies complicated by IUGR, whereas the four samples with aberrant SNU13 methylation were from IUGR (PL90), SGA (PL4002), and pre-eclampsia (PL2048, 2026)(Fig. 1a; Additional file 3).