For two loci, AIM1 and N4BP2L1, we found significant differences between the mean methylation levels for the IUGR group compared to controls (IUGR mean 66.5% vs control mean 63.0%, p 0.038; IUGR mean 52.5% vs control mean 48.6%, p 0.046, respectively). The gene discussed is N4BP2L1; the disease is fetal growth restriction.