Phex-specific models of XLH include Ska1 mice, which contain a chemically-induced point mutation in a splice donor site just after exon 8 [75], PhexK496X (Jrt) mice, which contain a stop codon at amino acid 496 [76], and Hyp-2J and Hyp-Duk mice [77], which contain larger frameshift deletions. This evidence concerns the gene SKA1 and X-linked hypophosphatemia.