NOTCH2 and colorectal cancer: To assess the role of miR-195-5p in colorectal cancer cells, we first examined the baseline miR-195-5p RNA and NOTCH2 mRNA levels in six cell lines (NCM460, HCT116, SW480, SW620, DLD-1, and HT29) by RT-qPCR (Additional file 3: Figure S1g-h).