GPT and hepatitis B virus infection: Recently infected patients may have elevated ALT levels prior to seroconversion, which warrants monitoring levels for early detection of new infections.19 Patients with unwarranted alteration of ALT, even if discrete elevations, should be investigated for hepatitis B and C. The validity or usefulness of monthly ALT dosing in patients with chronic hepatitis C infection resolved is unknown and there are no specific recommendations for this subgroup.21,22