Expression of RAGE and SOX2 (percentage of positive cells) was significantly higher in PCa lesions compared with prostatitis (p<0.01) and BPH (p<0.0001) and also was significantly higher in prostatitis compared with BPH lesions (p<0.01) (Table 1) (Figure 1 and 2). The gene discussed is SOX2; the disease is posterior cortical atrophy.