Among them, the novel antitumor active polypeptide has the characteristics of high affinity, strong specificity, and low adverse reaction, and most of them also have the property of selectively targeting tumor cells, and thus have very important development value in clinical application.13, 14 Chlorotoxin (CTX) is a short peptide of scorpion toxin isolated from the venom of the Israel golden carp, consisting of 36 amino acids.15 Studies have shown that CTX can bind to proteins on the surface of tumor cells, allowing them to specifically bind to tumor tissues. This evidence concerns the gene CYP27A1 and neoplasm.