Moreover, in i.v. animal model, the cells with Ki-67 positive in the tumor regions from the IL-6-treated group (inoculated by SPC-A-1) were increased when compared with those from other groups, including SPC-A-1 alone, BGC-823 alone, and the respective hUCMSCs or hAMSCs co-injection groups (Supplementary Fig. 2A). This evidence concerns the gene ATP2C1 and neoplasm.