SLC17A6 and alcohol dependence: In humans, an association of VGLUT2 genotype with alcohol dependence was found by an exploratory, haplotype-tag Single Nucleotide Polymorphisms (SNPs) study of the three VGLUT genes, such that the minor allele of the SNP rs2290045 in VGLUT2 was overrepresented (OR 1.660) in a sample of 191 women with alcohol dependence as compared to 184 healthy women [17].