INS and diabetes mellitus: Although the pathological mechanisms of diabetes appear to be closely associated with either a reduced production of insulin by the beta cells in the pancreas or the failures in transporting circulating glucose into the tissues via glucose receptors, the hyperglycemia and the subsequent complications involving the multiple organs and systems [4] could be managed by a modality of means including diet control, lifestyle modifications, and the effective therapeutic interventions including insulin administration [4, 5].